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Proteomics

High Throughput and Reproducible Protein Extraction

With the advancement of a tandem mass spectrometer and chromatography systems, researchers are now able to quantify many thousands of proteins in a single study. This has placed an ever-increasing focus on the quality of sample preparation prior to protein digestion, peptide separation, and LC-MS/MS. The old adage of garbage in = garbage out has never been more appropriate as it relates to a proteomic sample preparation. Sample disruption and protein extractions are typically the first steps in a proteomic study. The sample disruption procedure, instrument selection, and reagents can all impact the amount of protein extracted, resulting protein integrity and yield reproducibility. Omni International offers an assortment of homogenizer technology that covers a broad range of proteomic applications. For targeted studies focusing on organelle or membrane bound proteins, rotor-stator or manual homogenizers allow for the dissociation cellular material while maintaining the integrity of organelles. When coupled with disposable Omni TipTM generator probes, cross contamination is eliminated.

Protein profiling studies that required a high degree of reproducibility can benefit from Omni’s Bead Ruptor Bead Mill technology. Up to 96 samples can be disrupted simultaneously and with an identical degree of processing in contaminating free bead tubes. The high power of the Bead Ruptor homogenizers allows for disruption of very tough samples including skin, bone, and teeth.

Product Lines

  • Bead Ruptor 12

    Omni International "The Homogenizer Company" Model: Bead Ruptor 12

    High throughput and economical bead mill
    Power. 3 - 5 m/s | Vol. 0.25 mL - 5 mL | Samples. 1-12

    $4,995.00

    Application Notes

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    Product Brochure

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    Product Manuals

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    Omni Bead Ruptor 12 Bead Mill Homogenizer Manual
  • Bead Ruptor 24

    Omni International "The Homogenizer Company" Model: Bead Ruptor 24

    The most powerful and scalable bead mill available
    Power. 0.8 - 8 m/s | Vol. 0.25 mL - 50 mL | Samples. 1-96

  • Bead Ruptor 4

    Omni International "The Homogenizer Company" Model: Bead Ruptor 4

    Powerful performance in a compact design
    Power. 1-5 m/s | Vol. 0.25 mL - 5 mL | Samples. 1-4

    $1,995.00

    Product Brochure

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    Product Manuals

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    Application Notes

  • Bead Ruptor 24 Elite

    Omni International "The Homogenizer Company" Model: Bead Ruptor 24 Elite

    Next generation Bead Ruptor 24 with integrated touch screen and Optimate software.
    Power. 0.8 - 8 m/s | Vol. 0.25 mL - 50 mL | Samples. 1-96